Ulrika S H Simonsson Selected Research

Pharmaceutical Preparations

10/2022	Safety and pharmacokinetics-pharmacodynamics of a shorter tuberculosis treatment with high-dose pyrazinamide and rifampicin: a study protocol of a phase II clinical trial (HighShort-RP).
3/2022	Model-Informed Precision Dosing of Linezolid in Patients with Drug-Resistant Tuberculosis.
1/2022	Predictive Modeling to Study the Treatment-Shortening Potential of Novel Tuberculosis Drug Regimens, Toward Bundling of Preclinical Data.
1/2022	Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial.
1/2021	Superior Efficacy of a Bedaquiline, Delamanid, and Linezolid Combination Regimen in a Mouse Tuberculosis Model.
1/2021	Suboptimal moxifloxacin and levofloxacin drug exposure during treatment of patients with multidrug-resistant tuberculosis: results from a prospective study in China.
11/2020	Quantification of Natural Growth of Two Strains of Mycobacterium Marinum for Translational Antituberculosis Drug Development.
10/2020	A model-based analysis identifies differences in phenotypic resistance between in vitro and in vivo: implications for translational medicine within tuberculosis.
1/2020	Individualized Dosing With High Inter-Occasion Variability Is Correctly Handled With Model-Informed Precision Dosing-Using Rifampicin as an Example.
12/2018	Forecasting Clinical Dose-Response From Preclinical Studies in Tuberculosis Research: Translational Predictions With Rifampicin.

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Ulrika S H Simonsson Research Topics

Disease

33	Tuberculosis (Tuberculoses) 10/2022 - 11/2005
10	Pulmonary Tuberculosis 01/2022 - 11/2005
5	Body Weight (Weight, Body) 10/2019 - 02/2015
4	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 03/2022 - 01/2021
4	Infections 03/2022 - 12/2018
3	Postoperative Pain 01/2017 - 12/2015
2	Hemophilia A (Haemophilia) 10/2018 - 03/2018
1	Lung Diseases (Lung Disease) 03/2022
1	Atrial Fibrillation 01/2016
1	Pulmonary Embolism 12/2015
1	Venous Thrombosis (Deep-Vein Thrombosis) 12/2015
1	HIV Infections (HIV Infection) 04/2012
1	Pain (Aches) 06/2011
1	Malaria 06/2007
1	Nocturnal Enuresis (Bedwetting) 10/2006

Drug/Important Bio-Agent (IBA)

19	Pharmaceutical PreparationsIBA 10/2022 - 09/2013
15	Rifampin (Rifampicin)FDA LinkGeneric 10/2022 - 06/2008
7	Pyrazinamide FDA LinkGeneric 10/2022 - 09/2006
7	Isoniazid (Ftivazide)FDA LinkGeneric 12/2020 - 07/2011
4	Ethambutol (Myambutol)FDA LinkGeneric 10/2019 - 09/2011
3	Moxifloxacin (Avelox)FDA Link 01/2021 - 08/2012
3	edoxabanIBA 01/2016 - 11/2015
2	Linezolid (Zyvox)FDA Link 03/2022 - 01/2021
2	bedaquiline (R207910)IBA 01/2022 - 01/2021
2	Biomarkers (Surrogate Marker)IBA 10/2019 - 12/2018
2	Morphine (MS Contin)FDA LinkGeneric 05/2016 - 02/2015
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2016 - 12/2015
2	CreatinineIBA 01/2016 - 12/2015
2	rifapentine (Priftin)FDA Link 08/2012 - 11/2005
2	Ritonavir (Norvir)FDA Link 01/2012 - 10/2010
2	Lopinavir FDA Link 01/2012 - 10/2010
1	Anti-Bacterial Agents (Antibiotics)IBA 03/2022
1	Meropenem (Merrem)FDA LinkGeneric 01/2022
1	Carbapenems (Carbapenem Antibiotics)IBA 01/2022
1	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 01/2022
1	OPC-67683IBA 01/2021
1	Levofloxacin (Levaquin)FDA Link 01/2021
1	Antitubercular AgentsIBA 12/2020
1	Drug CombinationsIBA 01/2020
1	thiamine triphosphorate (TTP)IBA 10/2019
1	Factor VII (Proconvertin)IBA 03/2018
1	Factor VIII (Coagulation Factor VIII)IBA 03/2018
1	Opioid Analgesics (Opioids)IBA 01/2017
1	Analgesics (Analgesic Drugs)IBA 12/2015
1	Gatifloxacin (Zymar)FDA Link 09/2013
1	EnzymesIBA 04/2012
1	lopinavir-ritonavir drug combination (Kaletra)FDA Link 01/2012
1	Naproxen (Naprosyn)FDA LinkGeneric 06/2011
1	naproxen-n-butyl nitrateIBA 06/2011
1	Nevirapine (Viramune)FDA Link 01/2009
1	artemisinin (artemisinine)IBA 06/2007
1	Dosage Forms (Dosage Form)IBA 10/2006
1	Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric 10/2006

Therapy/Procedure

4	Therapeutics 03/2022 - 01/2009
2	Drug Tapering 01/2016 - 12/2015
2	Drug Therapy (Chemotherapy) 07/2011 - 01/2009
1	Duration of Therapy 01/2018